SCHEMBL81437

SCHEMBL81437

CCNC1=C2C(=O)c3ccccc3C(=O)C2=C(NCC)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.50
ALDH1A1 P00352 8/20 0.50
LMNA P02545 7/20 0.50
TDP1 Q9NUW8 5/20 0.50
HTT P42858 4/20 0.50
POLB P06746 4/20 0.50
MITF O75030 3/20 0.50
USP2 O75604 3/20 0.50
CDC25B P30305 2/20 0.42
PTPRC P08575 2/20 0.42
SMN1; SMN2 Q16637 9/20 0.41
PKM P14618 4/20 0.41
TP53 P04637 3/20 0.41
MAPK10 P53779 2/20 0.41
GAA P10253 2/20 0.41
GLA P06280 1/20 0.41
KLF5 Q13887 1/20 0.41
MAPK1 P28482 7/20 0.41
IDO1 P14902 1/20 0.40
APAF1 O14727 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966417 0.76 MAPT (0.50) MAPTALDH1A1LMNATDP1HTT
SCHEMBL6687252 0.70 MAPT (0.61) MAPTALDH1A1LMNATDP1HTT
SCHEMBL30678386 0.69 MEN1 (0.60) MAPTALDH1A1LMNATDP1HTT
SCHEMBL29366166 0.69 MEN1 (0.60) MAPTALDH1A1LMNATDP1HTT
SCHEMBL78525 0.69 MEN1 (0.60) MAPTALDH1A1LMNATDP1HTT
SCHEMBL17347045 0.69 MAPT (0.59) MAPTALDH1A1LMNATDP1HTT
Anthraquinone SCHEMBL28296916 0.67 CDC25B (0.57) MAPTALDH1A1LMNATDP1HTT
SCHEMBL14003716 0.67 CDC25B (0.73) MAPTALDH1A1LMNATDP1HTT
SCHEMBL30587679 0.67 MAOA (0.68) MAPTALDH1A1LMNATDP1HTT
SCHEMBL15690333 0.67 MAOA (0.68) MAPTALDH1A1LMNATDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705007-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2012-06-06 EP disclosed
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-7662540-B2 Support, photosensitive layer, protective film; photosensitive layer and protective film being formed in this order on support, wherein number of fish-eyes each having area of 2,000 mu m2 or more and maximum height measured from film surface of 1 mu m to 7 mu m residing in film is 50/m2-1,000/m2 FUJIFILM CORPORATION (JP) 2010-02-16 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
US-7556911-B2 Titanocene based compound, photosensitive composition, photosensitive transfer sheet and pattern forming method FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
EP-1765592-B1 METHOD FOR MAKING NEGATIVE-WORKING HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2009-01-28 EP disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
US-7402374-B2 Method for colored image formation FUJIFILM CORPORATION (JP) 2008-07-22 US disclosed
US-20080118867-A1 Pattern Forming Material, Pattern Forming Apparatus, And Pattern Forming Process ASAHI KASEI E-MATERIALS CORPORATION (JP) 2008-05-22 US disclosed
US-20080113302-A1 Pattern Forming Process FUJIFILM CORPORATION (JP) 2008-05-15 US disclosed
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4271251-A LEUCO DYE, PHOTOOXIDIZER, 2,4-DIHYDROXY-BENZALDOXIME FUJI PHOTO FILM CO., LTD. (JP) 1981-06-02 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed