SCHEMBL8144013

SCHEMBL8144013

CN1C(=O)C(=O)N(CC(=O)O)C1=O

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
S1PR2 O95136 1/20 0.43
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 3/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 1/20 0.38
AKR1B1 P15121 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14574061 0.82 CA12 (0.40) CA12CA9S1PR2KMT2AALDH1A1
SCHEMBL6636236 0.78 F2 (0.50) CA12CA9KMT2AALDH1A1TSHR
SCHEMBL8144003 0.76 KMT2A (0.46) CA12CA9KMT2AALDH1A1PKM
SCHEMBL9322628 0.75 GSK3A (0.56) KMT2AALDH1A1MEN1MAPTHSD17B10
SCHEMBL8144099 0.74 ALDH1A1 (0.48) CA12CA9KMT2AALDH1A1KDM4E
SCHEMBL13931167 0.74 HTT (0.49) CA12CA9KMT2AALDH1A1PKM
SCHEMBL7591274 0.74 PTGS1 (0.46) KMT2A
SCHEMBL12220480 0.72 CA12 (0.42) CA12CA9KMT2AALDH1A1TSHR
SCHEMBL11937035 0.71 CA12 (0.45) CA12CA9KMT2AALDH1A1TSHR
SCHEMBL13170329 0.71 CA12 (0.41) CA12CA9KMT2AALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10182460-A None JP disclosed
CN-119192677-B Composite heat stabilizer for PVC and preparation method 深圳凯奇化工有限公司 2025-06-24 CN disclosed
CN-119192677-A Composite heat stabilizer for PVC and preparation method 深圳凯奇化工有限公司 2024-12-27 CN disclosed
US-6040326-A 3-deoxyglucosone production inhibitor NIPPON ZOKI PHARMACEUTICALS CO., LTD. (JP) 2000-03-21 US disclosed
EP-0855182-A1 3-Deoxyglucosone production inhibitor NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
JP-H10182460-A 3-DEOXYGLUCOSONE GENERATION INHIBITOR NIPPON ZOKI PHARMACEUT CO LTD 1998-07-07 JP disclosed
EP-0353198-B1 Parabanic acid derivatives and pharmaceutical compositions containing them NIPPON ZOKI PHARMACEUTICAL CO (JP) 1994-02-02 EP disclosed
US-4985453-A DIABETES TREATMENT NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1991-01-15 US disclosed
EP-0353198-A1 Parabanic acid derivatives and pharmaceutical compositions containing them NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1990-01-31 EP disclosed