Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144003 | 0.80 | KMT2A (0.46) | CA12CA9NPC1RAB9AKMT2A | |
| SCHEMBL8144013 | 0.78 | CA12 (0.44) | CA12CA9KMT2ATSHRALDH1A1 | |
| SCHEMBL8144099 | 0.78 | ALDH1A1 (0.48) | CA12CA9KMT2AALDH1A1 | |
| SCHEMBL7591274 | 0.77 | PTGS1 (0.46) | KMT2A | |
| SCHEMBL12220480 | 0.77 | CA12 (0.42) | CA12CA9NPC1KMT2ATSHR | |
| SCHEMBL11937035 | 0.76 | CA12 (0.45) | CA12CA9KMT2ATSHRALDH1A1 | |
| SCHEMBL13170329 | 0.75 | CA12 (0.41) | CA12CA9KMT2ATSHRALDH1A1 | |
| Phosphonic Acid SCHEMBL9168552 | 0.75 | F2 (0.57) | F2ELANECTSGCTRCNPC1 | |
| SCHEMBL8150342 | 0.71 | MAPT (0.68) | RAB9AKMT2AALDH1A1 | |
| SCHEMBL8143584 | 0.71 | KMT2A (0.76) | F2ELANECTSGCTRCCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423356-A2 | NOVEL AMINOBENZOEPHENONES | Leo Pharma A/S (DK) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | disclosed |
| EP-0718289-B1 | Novel parabanic acid derivatives as aldose reductase inhibitors | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5681843-A | ANTIDIABETIC; ALDOSE REDUCTASE INHIBITOR WITHOUT SUBSTANTIALLY INHIBITING ALDEHYDE REDUCATASE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0718289-A1 | Novel parabanic acid derivatives as aldose reductase inhibitors | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |