Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136570 | 0.80 | ADK (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL8139423 | 0.78 | ADORA1 (0.62) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL31120339 | 0.76 | ADORA1 (0.74) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL8214241 | 0.72 | KDM4E (0.70) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL6255131 | 0.70 | ADORA1 (0.76) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL31120351 | 0.69 | ADORA1 (0.83) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL8191929 | 0.69 | KDM4E (0.61) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL28687495 | 0.69 | MAPK14 (0.77) | ADORA1ADORA2AKDM4EALDH1A1LMNA | |
| SCHEMBL2039835 | 0.67 | ADK (0.58) | KDM4EALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL13098519 | 0.67 | ADORA1 (0.56) | ADORA1ADORA2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |
| EP-0989986-A1 | 5,7-DISUBSTITUTED 4-AMINOPYRIDO 2,3-D]PYRIMIDINE COMPOUNDS AND THEIR USE AS ADENOSINE KINASE INHIBITORS | Abbott Laboratories (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998046605-A1 | 5,7-DISUBSTITUTED 4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS AND THEIR USE AS ADENOSINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | disclosed |