Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145018 | 1.00 | KDM4C (0.38) | KDM4CPOLBKDM4ELMNAALDH1A1 | |
| SCHEMBL6971583 | 0.91 | MEN1 (0.38) | KDM4CPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL6971586 | 0.91 | MEN1 (0.38) | KDM4CPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL6969291 | 0.77 | ALDH1A1 (0.39) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL6969287 | 0.77 | ALDH1A1 (0.39) | POLBKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL6975883 | 0.73 | KDM4E (0.43) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6964986 | 0.71 | RAB9A (0.39) | POLBKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL6973007 | 0.70 | KDM4E (0.39) | POLBKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL6973003 | 0.70 | KDM4E (0.39) | POLBKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL6967416 | 0.70 | PARP1 (0.35) | POLBLMNAHPGDMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011028-A | Cyclic amidino agents useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 2000-01-04 | — | — | US | disclosed |