Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | STS | P08842 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145956 | 0.91 | KDM4E (0.64) | HRH3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6691697 | 0.85 | HSD17B1 (0.74) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL10134113 | 0.85 | HSD17B1 (0.74) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL14044784 | 0.85 | HSD17B1 (0.74) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL11672003 | 0.85 | HSD17B1 (0.74) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL7755033 | 0.85 | HSD17B1 (0.74) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL8145247 | 0.85 | HRH3 (0.71) | HRH3STSKCNH2SHBG | |
| SCHEMBL6696320 | 0.84 | HSD17B1 (0.77) | KDM4EALDH1A1LMNAMAPTHSD17B1 | |
| SCHEMBL14377634 | 0.84 | KDM4E (0.72) | HRH3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9633204 | 0.84 | KDM4E (0.75) | KDM4EALDH1A1LMNAMAPTHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | claimed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | claimed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | disclosed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |