Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527873 | 0.87 | F10 (0.44) | F10MAOBMAOAGRM2 | |
| SCHEMBL8145434 | 0.84 | F10 (0.56) | F10MAOBMAOAGRM2 | |
| SCHEMBL6529666 | 0.83 | F10 (0.64) | F10MAOBCYP11B2MAOACYP11B1 | |
| SCHEMBL8131862 | 0.83 | F10 (0.61) | F10MAOBCYP11B2MAOAGRM2 | |
| SCHEMBL6529624 | 0.83 | F10 (0.61) | F10MAOBCYP11B2MAOAGRM2 | |
| SCHEMBL6529626 | 0.83 | F10 (0.61) | F10MAOBCYP11B2MAOAGRM2 | |
| SCHEMBL3829363 | 0.83 | MAOB (0.41) | F10MAOBMAOAGRM2 | |
| SCHEMBL8118120 | 0.83 | MAOB (0.41) | F10MAOBCYP11B2MAOAGRM2 | |
| SCHEMBL3829368 | 0.83 | MAOB (0.41) | F10MAOBMAOAGRM2 | |
| SCHEMBL591031 | 0.81 | SIGMAR1 (0.46) | MAOBMAOAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049692-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037641-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |