SCHEMBL814569

SCHEMBL814569

O=C1NC(c2cccc(Cl)c2)=C2C(=O)NC(c3cccc(Cl)c3)=C12

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 9/20 0.50
GSK3A P49840 3/20 0.49
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
BRDT Q58F21 1/20 0.47
TDP2 O95551 2/20 0.46
PGR P06401 3/20 0.45
BRD4 O60885 1/20 0.45
CCNA2 P20248 1/20 0.44
CDK2 P24941 1/20 0.44
CCNA1 P78396 1/20 0.44
NOTUM Q6P988 1/20 0.44
PARP10 Q53GL7 1/20 0.43
PARP11 Q9NR21 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607586 0.95 GSK3B (0.54) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL13204641 0.93 GSK3B (0.52) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL13222114 0.89 GSK3B (0.43) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL13336739 0.89 PGR (0.46) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL15382625 0.85 PARP1 (0.57) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL15382624 0.82 GSK3B (0.48) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL12424911 0.79 CES1 (0.36) GSK3BGSK3APGR
SCHEMBL30999908 0.79 GSK3B (0.55) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL934146 0.79 GSK3B (0.65) GSK3BGSK3AADORA2AADORA1BRDT
SCHEMBL7750654 0.79 GSK3B (0.43) GSK3BPGRPARP10PARP11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199052-B1 PROCESS FOR PRODUCTION OF INJECTION-MOLDED ARTICLE OF POLYLACTIC ACID RESIN KAO CORP (JP) 2014-01-22 EP disclosed
US-8318052-B2 Diketopyrrolopyrrole cocrystals with high transparency CLARIANT FINANCE (BVI) LIMITED (VG) 2012-11-27 US disclosed
EP-1502932-B1 RESIN COMPOSITION SONY CORP (JP) 2012-07-11 EP disclosed
EP-2261286-B1 Resin composition SONY CORP (JP) 2012-06-06 EP disclosed
US-8062574-B2 Process for production of injection-molded article of polylactic acid resin KAO CORPORATION (JP) 2011-11-22 US disclosed
US-8003712-B2 Resin composition and process for producing resin molding SONY CORPORATION (JP) 2011-08-23 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
EP-2261286-A1 Resin composition Sony Corporation (JP) 2010-12-15 EP disclosed
US-7790782-B2 Resin composition SONY CORPORATION (JP) 2010-09-07 US disclosed
EP-0690057-A1 Crystal modification of a diketopyrrolopyrrole pigment CIBA-GEIGY AG (CH) 1996-01-03 EP disclosed
US-5382485-A Process for storing information CIBA-GEIGY CORPORATION (US) 1995-01-17 US disclosed
EP-0560727-A1 Information storage method CIBA-GEIGY AG (CH) 1993-09-15 EP disclosed
EP-0133156-B1 1,4-DIKETOPYRROLO-(3,4-C) PYRROLES CIBA-GEIGY AG (CH) 1991-07-10 EP disclosed
EP-0256983-B1 Solid solutions of pyrrolo-[3,4-c]pyrroles CIBA-GEIGY AG (CH) 1989-09-27 EP disclosed
US-4783540-A Solid solutions of pyrrolo-(3,4-C)-pyrrols CIBA-GEIGY CORPORATION (US) 1988-11-08 US disclosed
EP-0256983-A1 Solid solutions of pyrrolo-[3,4-c]pyrroles CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
US-4666455-A Compositions pigmented with N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1987-05-19 US disclosed
US-4585878-A N-substituted 1,4-diketopyrrolo-[3,4-c]-pyrroles CIBA-GEIGY CORPORATION (US) 1986-04-29 US disclosed
EP-0133156-A2 1,4-Diketopyrrolo-(3,4-c) pyrroles CIBA-GEIGY AG (CH) 1985-02-13 EP disclosed