Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.55 |
| ▸ | GSK3A | P49840 | 5/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
| ▸ | STK10 | O94804 | 2/20 | 0.48 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934146 | 0.85 | GSK3B (0.65) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL3820693 | 0.84 | GSK3B (0.63) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL4079370 | 0.82 | GSK3B (0.57) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL6858139 | 0.82 | STK10 (0.46) | GSK3BGSK3ASTK10SLKPGR | |
| SCHEMBL30999976 | 0.82 | GSK3B (0.59) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL3818590 | 0.81 | GSK3B (0.51) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL18049417 | 0.81 | CAMK2D (0.55) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL3820556 | 0.81 | GSK3B (0.52) | GSK3BGSK3AADORA2AADORA1BRDT | |
| SCHEMBL187281 | 0.80 | GSK3B (0.53) | GSK3BSTK10SLK | |
| SCHEMBL3819171 | 0.80 | GSK3B (0.51) | GSK3BGSK3AADORA2AADORA1BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024163852-A1 | HISTIDINE KINASE INHIBITORS AS ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-08-08 | — | — | WO | disclosed |