Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560438 | 0.81 | KMT2A (0.44) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL11658726 | 0.81 | KMT2A (0.44) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL9330327 | 0.75 | KMT2A (0.37) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL5468896 | 0.74 | CYP2D6 (0.48) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL3962160 | 0.71 | NOS3 (0.49) | CYP1A2ALDH1A1TSHRSIGMAR1NOS3 | |
| SCHEMBL272549 | 0.71 | — | — | |
| SCHEMBL3637981 | 0.71 | — | — | |
| SCHEMBL18531660 | 0.71 | CYP2D6 (0.50) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL9517696 | 0.71 | CYP2D6 (0.50) | KMT2ACYP2D6MEN1LMNATP53 | |
| SCHEMBL8146619 | 0.71 | CYP2D6 (0.50) | KMT2ACYP2D6MEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011028-A | Cyclic amidino agents useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 2000-01-04 | — | — | US | disclosed |