Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138711 | 0.85 | MAPK8 (0.42) | KDM4ENAMPTMAPTKDM4C | |
| SCHEMBL8146168 | 0.76 | PRKAG1 (0.40) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL24915548 | 0.75 | KDM4E (0.45) | HTR3AKDM4EGAAMTNR1AMTNR1B | |
| SCHEMBL905833 | 0.74 | HSD17B10 (0.40) | HTR3AKDM4EGAANAMPTMAPT | |
| SCHEMBL5678098 | 0.71 | DYRK1A (0.38) | KDM4EGAASMN1; SMN2 | |
| Fumaric Acid SCHEMBL8146150 | 0.71 | HTR3A (0.40) | HTR3AKDM4EGAAMTNR1AMTNR1B | |
| Fumaric Acid SCHEMBL8146156 | 0.71 | HTR3A (0.40) | HTR3AKDM4EGAAMTNR1AMTNR1B | |
| SCHEMBL12582640 | 0.69 | HTR3A (0.54) | HTR3AKDM4EGAANAMPTMAPT | |
| SCHEMBL5990554 | 0.69 | KDM4E (0.34) | HTR3AKDM4EMTNR1AMTNR1BNAMPT | |
| SCHEMBL1964671 | 0.68 | HTR3A (0.55) | HTR3AKDM4EGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000012482-A2 | INDAZOLE DERIVATIVES WITH 5-HT2 RECEPTOR ACTIVITY | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |