Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568908 | 0.88 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL27334379 | 0.74 | AKR1B1 (0.61) | AKR1B1 | |
| SCHEMBL10487554 | 0.70 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10487538 | 0.69 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL3696812 | 0.67 | ACHE (0.33) | AKR1B1 | |
| SCHEMBL10487428 | 0.67 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL7573710 | 0.67 | KIF11 (0.33) | — | |
| SCHEMBL8143402 | 0.67 | KIF11 (0.33) | — | |
| SCHEMBL10487495 | 0.66 | AKR1B1 (0.59) | AKR1B1 | |
| SCHEMBL10487502 | 0.66 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124284-A | REDUCED SIDE EFFECTS | GLAXO WELLCOME INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-5872118-A | RELAXATION OF SKELETAL MUSCLE IN SPASTIC, HYPERTONIC AND HYPERKINETIC CONDITIONS | GLAXO WELLCOME INC. (US) | 1999-02-16 | — | — | US | disclosed |