Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 12/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20024708 | 0.89 | FBP1 (0.75) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL10590114 | 0.86 | PPARA (0.66) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL6780080 | 0.85 | OPRK1 (0.65) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11548436 | 0.83 | PPARA (0.76) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL3903999 | 0.83 | PPARA (0.76) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL21188244 | 0.83 | PPARA (0.66) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14290102 | 0.83 | FBP1 (0.47) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11785569 | 0.82 | FBP1 (0.67) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11785564 | 0.82 | FBP1 (0.67) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL814353 | 0.82 | FBP1 (0.68) | PPARAABCB11CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20190225597-A1 | PYRROLIDINE DERIVATIVES AS PPAR AGONISTS | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2019-07-25 | — | — | US | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-9155690-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-10-13 | — | — | US | disclosed |
| US-9155690-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-10-13 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-4233298-A | ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | ORCHIMED SA (CH) | 1980-11-11 | — | — | US | disclosed |
| US-4214094-A | ANTILIPEMIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-22 | — | — | US | disclosed |
| US-4212976-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4163859-A | ANTILIPEMIC, FUNGICIDES, BACTERICIDES | G. D. SEARLE & CO. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4058552-A | HYPOCHOLESTEROLEMIA, HYPOLIPIDEMIA | ORCHIMED SA (CH) | 1977-11-15 | — | — | US | disclosed |
| US-4057637-A | RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-3994955-A | Substituted phenoxydialkylacetic acids and esters | G. D. SEARLE & CO. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3971797-A | ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |
| US-3968117-A | CARDIOVASCULAR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3959296-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | PPARA 2/4885ABCB11 4713/4885CYP1A2 299/4885 |
| US-20190225597-A1 | PYRROLIDINE DERIVATIVES AS PPAR AGONISTS | PPARD, PPARA, PPARG | PPARA 2/4885ABCB11 85/4885CYP1A2 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.