Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467209 | 0.97 | POLB (0.39) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL10965102 | 0.86 | POLB (0.33) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9563941 | 0.82 | POLB (0.35) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL4833943 | 0.82 | POLB (0.35) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9787544 | 0.82 | LMNA (0.35) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9787543 | 0.82 | LMNA (0.35) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9581406 | 0.80 | POLB (0.44) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL6563535 | 0.80 | POLB (0.33) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| SCHEMBL9787658 | 0.80 | LMNA (0.34) | POLBTDP1HSD17B10ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9787533 | 0.80 | LMNA (0.34) | POLBTDP1HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000000461-A1 | TETRAIODOTEREPHTHALAMIDE POLYHYDROXYLATED DERIVATIVES, PREPARATION METHOD AND USE IN RADIOLOGY | GUERBET S.A. (FR) | 2000-01-06 | — | — | WO | disclosed |