SCHEMBL8148202

SCHEMBL8148202

c1ccc2c(Nc3ccc(Nc4c5ccccc5cc5ccccc45)cc3)c3ccccc3cc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 10/20 0.54
KMT2A Q03164 4/20 0.49
MEN1 O00255 2/20 0.49
POLB P06746 2/20 0.46
RAD52 P43351 2/20 0.46
GFER P55789 1/20 0.46
ALDH1A1 P00352 4/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
CYP3A4 P08684 2/20 0.45
ATM Q13315 2/20 0.44
CDC25B P30305 2/20 0.43
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
RECQL P46063 2/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287371 0.93 KDM1A (0.63) KDM1AKMT2AMEN1POLBRAD52
SCHEMBL28425271 0.90 KDM1A (0.50) KDM1AKMT2AMEN1POLBRAD52
SCHEMBL18134977 0.90 KDM1A (0.66) KDM1AKMT2AMEN1POLBALDH1A1
SCHEMBL2837802 0.87 ALDH1A1 (0.48) KDM1AKMT2AMEN1ALDH1A1HPGD
SCHEMBL14378552 0.87 ALOX5 (0.47) KDM1AKMT2AMEN1POLBRAD52
SCHEMBL13446159 0.85 CYP11B1 (0.44) KDM1AKMT2AMEN1POLBRAD52
SCHEMBL28528794 0.85 KMT2A (0.69) KDM1AKMT2AMEN1POLBRAD52
SCHEMBL19763117 0.85 KDM1A (0.60) KDM1AKMT2AMEN1HPGDCDC25B
SCHEMBL8148203 0.81 KDM1A (0.46) KDM1AKMT2AMEN1POLBALDH1A1
SCHEMBL27575497 0.80 KDM1A (0.49) KDM1AKMT2AMEN1POLBRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed