Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | IL6 | P05231 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GLUL | P15104 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885697 | 0.82 | CYP3A4 (0.52) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL238494 | 0.81 | LMNA (0.60) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL238493 | 0.81 | LMNA (0.60) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL3748497 | 0.79 | CYP19A1 (0.53) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL5203283 | 0.78 | CYP19A1 (0.50) | CYP19A1 | |
| SCHEMBL8148330 | 0.76 | CYP19A1 (0.53) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| Propionic Acid SCHEMBL29224763 | 0.74 | CYP19A1 (0.85) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL6706306 | 0.73 | LMNA (0.58) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| SCHEMBL9015138 | 0.73 | CYP19A1 (0.69) | CYP19A1LMNAMAPTCYP3A4HSD17B10 | |
| Acetone SCHEMBL9504391 | 0.73 | CYP19A1 (0.69) | CYP19A1LMNAMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147066-A | Use of antimineralocorticoid compounds against drug withdrawal syndrome | Roussel, Hoechst Marion (FR) | 2000-11-14 | — | — | US | disclosed |