Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154891 | 0.98 | HTR1A (0.55) | HTR1ADRD2HTR2A | |
| SCHEMBL8151673 | 0.94 | — | — | |
| SCHEMBL8156696 | 0.93 | — | — | |
| SCHEMBL8150735 | 0.80 | HTR1A (0.44) | HTR1ADRD2HTR2A | |
| SCHEMBL6766552 | 0.80 | HTR1A (0.47) | HTR1A | |
| SCHEMBL8150191 | 0.80 | HTR1A (0.61) | HTR1A | |
| SCHEMBL8306321 | 0.79 | HTR1A (0.47) | HTR1ADRD2 | |
| SCHEMBL8306292 | 0.79 | HTR1A (0.47) | HTR1ADRD2 | |
| SCHEMBL8143460 | 0.77 | HTR1A (0.61) | HTR1ADRD2HTR2A | |
| SCHEMBL8156077 | 0.77 | HTR1A (0.67) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673375-B1 | FUSED BENZO COMPOUNDS | LUNDBECK & CO AS H (DK) | 1999-02-24 | — | — | EP | claimed |
| US-6140331-A | FOR TREATING ANXIETY DISORDERS, DEPRESSION, PSYCHOSIS, IMPULSE CONTROL DISORDERS, ALCOHOL ABUSE, ISCHAEMIC DISEASES, CARDIOVASCULAR DISORDERS, SIDE EFFECTS INDUCED BY CONVENTIONAL ANTIPSYCHOTIC AGENTS AND SENILE DEMENTIA | H. LUNDBECK A/S (DK) | 2000-10-31 | — | — | US | disclosed |
| EP-0673375-B1 | FUSED BENZO COMPOUNDS | LUNDBECK & CO AS H (DK) | 1999-02-24 | — | — | EP | disclosed |