SCHEMBL8148554

SCHEMBL8148554

C=C(C)C(=O)OC1CCN(C(=O)/C=C/c2ccc([N+](=O)[O-])cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
GPR183 P32249 1/20 0.51
POLB P06746 1/20 0.49
ITGB2 P05107 1/20 0.47
ICAM1 P05362 1/20 0.47
ITGAL P20701 1/20 0.47
CCR2 P41597 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8149173 0.88 ITGB2 (0.66) ALDH1A1SMN1; SMN2POLBITGB2ICAM1
SCHEMBL8154799 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2GPR183POLBITGB2
SCHEMBL8155116 0.85 MAPT (0.56) ALDH1A1SMN1; SMN2GPR183NPC1RAB9A
SCHEMBL8139781 0.85 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2GPR183MEN1KMT2A
SCHEMBL8140664 0.85 POLB (0.47) ALDH1A1SMN1; SMN2POLBITGB2ICAM1
SCHEMBL8146687 0.84 GAA (0.56) ALDH1A1SMN1; SMN2GPR183ITGALCCR2
SCHEMBL8141106 0.84 RAB9A (0.59) ALDH1A1SMN1; SMN2GPR183POLBMEN1
SCHEMBL8149790 0.84 ITGB2 (0.50) SMN1; SMN2POLBITGB2ICAM1ITGAL
SCHEMBL8434432 0.84 MAPT (0.57) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL8152434 0.84 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2GPR183NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE36625-E Linear and cyclic polymers or oligomers having a photoreactive ethene group ROLIC AG (CH) 2000-03-21 US disclosed
US-5539074-A LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS HOFFMANN-LA ROCHE INC. (US) 1996-07-23 US disclosed