Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | DNTT | P04053 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16969274 | 0.88 | HTT (0.45) | HTTTSHRSMN1; SMN2ALOX5DNTT | |
| SCHEMBL25118477 | 0.86 | ALOX5 (0.47) | HTTTSHRSMN1; SMN2ALOX5DNTT | |
| SCHEMBL12054901 | 0.85 | HTT (0.39) | HTTTSHRSMN1; SMN2 | |
| SCHEMBL8147761 | 0.85 | HTT (0.39) | HTTTSHRSMN1; SMN2 | |
| SCHEMBL10887383 | 0.84 | ALDH1A1 (0.52) | HTTTSHRSMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL3493177 | 0.84 | ALDH1A1 (0.52) | HTTTSHRSMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL9293726 | 0.84 | HTT (0.38) | HTTTSHRSMN1; SMN2ALOX5CYP1A2 | |
| SCHEMBL9293721 | 0.84 | HTT (0.40) | HTTTSHRSMN1; SMN2ALOX5DNTT | |
| SCHEMBL3491244 | 0.84 | ALDH1A1 (0.52) | HTTTSHRSMN1; SMN2ALOX5ALDH1A1 | |
| SCHEMBL10628247 | 0.84 | ALDH1A1 (0.52) | HTTTSHRSMN1; SMN2ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |