Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 16/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139341 | 0.89 | ADK (0.57) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2049699 | 0.79 | ADK (0.58) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8152829 | 0.74 | ADK (0.53) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8152909 | 0.73 | ADK (0.52) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8149937 | 0.72 | ADK (0.48) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8148277 | 0.71 | ADK (0.50) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8154196 | 0.70 | ADK (0.63) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8140518 | 0.70 | ADK (0.48) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8134712 | 0.69 | ADK (0.59) | ADKKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2053382 | 0.67 | ADK (0.73) | ADKKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989986-A1 | 5,7-DISUBSTITUTED 4-AMINOPYRIDO 2,3-D]PYRIMIDINE COMPOUNDS AND THEIR USE AS ADENOSINE KINASE INHIBITORS | Abbott Laboratories (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998046605-A1 | 5,7-DISUBSTITUTED 4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS AND THEIR USE AS ADENOSINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | disclosed |