SCHEMBL8148786

SCHEMBL8148786

CCC(CBr)OP(=O)(O)OC(CC)CBr

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.34
SMPD1 P17405 3/20 0.31
LPAR1 Q92633 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP8 P22894 1/20 0.30
CA9 Q16790 1/20 0.30
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21986461 0.86 SMPD1 (0.39) LAP3SMPD1LPAR1CA12CA1
SCHEMBL3814144 0.85 LAP3 (0.40) LAP3SMPD1LPAR1CA12CA1
SCHEMBL21986458 0.81 TSHR (0.32)
SCHEMBL5850899 0.77
SCHEMBL3818188 0.77 FDPS (0.44) LAP3SMPD1FDPS
SCHEMBL15264225 0.77 LAP3 (0.34) LAP3SMPD1CA12CA1CA2
SCHEMBL13557332 0.74 LAP3 (0.36) LAP3SMPD1CA12CA1CA2
SCHEMBL3820802 0.74 FDPS (0.48) LAP3SMPD1CA1CA2FDPS
SCHEMBL18250385 0.73 TSHR (0.40) LAP3SMPD1CA12CA1CA2
SCHEMBL1203366 0.73 BTN3A1 (0.39) LAP3SMPD1LPAR1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030877-A1 FLAME AND BLOOM RESISTANT POLYOLEFIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 2000-08-30 EP disclosed
WO-2000037552-A1 ADDITIVE CONCENTRATES FOR OLEFINIC POLYMERS GREAT LAKES CHEMICAL CORPORATION (US) 2000-06-29 WO disclosed
WO-1999025763-A1 FLAME AND BLOOM RESISTANT POLYOLEFIN COMPOSITIONS GREAT LAKES CHEMICAL CORPORATION (US) 1999-05-27 WO disclosed