Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427586 | 1.00 | PDE4B (0.40) | PDE4BPTPN1ERN1MAOAHTT | |
| SCHEMBL7197233 | 0.96 | PDE4B (0.43) | PDE4BPTPN1ERN1MAOAHTT | |
| SCHEMBL2022907 | 0.88 | PTPN1 (0.40) | PDE4BPTPN1ERN1KMT2A | |
| SCHEMBL2025509 | 0.87 | PTPN1 (0.35) | PDE4BPTPN1MEN1KMT2ANPC1 | |
| SCHEMBL2024557 | 0.84 | DRD2 (0.31) | PDE4BPTPN1 | |
| SCHEMBL2023924 | 0.84 | PTPN1 (0.38) | PDE4BPTPN1ERN1MEN1KMT2A | |
| SCHEMBL8161413 | 0.84 | PTPN1 (0.38) | PDE4BPTPN1ERN1MEN1KMT2A | |
| SCHEMBL2024860 | 0.80 | PTPN1 (0.36) | PDE4BPTPN1ERN1 | |
| SCHEMBL29394265 | 0.79 | ALDH1A1 (0.54) | PDE4BPTPN1L3MBTL1NPC1RAB9A | |
| SCHEMBL5863561 | 0.79 | ALDH1A1 (0.54) | PDE4BPTPN1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |