Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18457667 | 0.83 | CA12 (0.42) | TDP1LMNACA12CA1CA9 | |
| SCHEMBL375752 | 0.83 | CA12 (0.43) | TDP1LMNACA12CA1CA9 | |
| SCHEMBL21608 | 0.82 | LMNA (0.40) | HSD17B10TDP1LMNACA12CA1 | |
| SCHEMBL1261147 | 0.81 | ALDH1A1 (0.42) | LMNACA12CA1CA9MMP1 | |
| SCHEMBL9273427 | 0.81 | LMNA (0.33) | LMNACA12CA1CA9MMP1 | |
| SCHEMBL375409 | 0.79 | CA12 (0.53) | LMNACA12CA1CA9MMP1 | |
| SCHEMBL1038718 | 0.79 | TDP1 (0.33) | TDP1LMNACA12CA1CA9 | |
| Acetic Acid SCHEMBL27406507 | 0.78 | LMNA (0.37) | TDP1LMNACA12CA1CA9 | |
| SCHEMBL27477398 | 0.78 | — | — | |
| SCHEMBL1261154 | 0.78 | CA12 (0.38) | LMNACA12CA1CA9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6041157-A | Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same | GOETZ FREDERICK JAMES (US) | 2000-03-21 | — | — | US | disclosed |