Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366981 | 0.80 | BBOX1 (0.44) | KDM4EALDH1A1AKR1B1HPGDHSD17B10 | |
| SCHEMBL29494080 | 0.79 | HPRT1 (0.47) | KDM4EALDH1A1AKR1B1GAAHPGD | |
| SCHEMBL413130 | 0.79 | HPRT1 (0.47) | KDM4EALDH1A1AKR1B1GAAHPGD | |
| SCHEMBL7596368 | 0.78 | TSHR (0.42) | G6PDALDH1A1AKR1B1HSD17B10 | |
| SCHEMBL173509 | 0.78 | TSHR (0.42) | G6PDALDH1A1AKR1B1HSD17B10 | |
| SCHEMBL11190798 | 0.78 | TSHR (0.42) | G6PDALDH1A1AKR1B1HSD17B10 | |
| SCHEMBL1627739 | 0.77 | KCNJ11 (0.43) | G6PDKDM4EALDH1A1AKR1B1HSD17B10 | |
| SCHEMBL27140016 | 0.77 | AKR1B1 (0.50) | ALDH1A1AKR1B1GAAHPGDHSD17B10 | |
| SCHEMBL680370 | 0.77 | AKR1B1 (0.40) | G6PDKDM4EALDH1A1AKR1B1HSD17B10 | |
| Acetic Acid SCHEMBL29643381 | 0.75 | S1PR4 (0.40) | G6PDKDM4EALDH1A1AKR1B1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083758-A | CONTACTING ARRAY OF PEPTIDES, INCLUDING BINDING OR SIGNALING GROUP AND COUPLED TO A SOLID PHASE SUPPORT, WITH SOLUTION CONTAINING KNOWN CONCENTRATION OF METAL AND MONITORING FLUORESCENCE OF EACH OF THE PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-04 | — | — | US | claimed |
| US-6083758-A | CONTACTING ARRAY OF PEPTIDES, INCLUDING BINDING OR SIGNALING GROUP AND COUPLED TO A SOLID PHASE SUPPORT, WITH SOLUTION CONTAINING KNOWN CONCENTRATION OF METAL AND MONITORING FLUORESCENCE OF EACH OF THE PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2000-07-04 | — | — | US | disclosed |