Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 5/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150570 | 0.90 | KDM4E (0.37) | DAGLAABHD6HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL8151687 | 0.88 | DAGLA (0.33) | DAGLAABHD6HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL8138505 | 0.88 | DAGLA (0.35) | DAGLAABHD6HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL8154288 | 0.87 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1NPC1 | |
| SCHEMBL8144523 | 0.87 | KDM4E (0.45) | DAGLAABHD6ALDH1A1NPC1RAB9A | |
| SCHEMBL8150595 | 0.86 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1 | |
| SCHEMBL8154720 | 0.86 | DAGLB (0.37) | DAGLAABHD6HCRTR2HCRTR1 | |
| SCHEMBL8151105 | 0.84 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1NPC1 | |
| SCHEMBL8136076 | 0.84 | KDM4E (0.38) | DAGLAABHD6HCRTR2HCRTR1ALDH1A1 | |
| SCHEMBL8142375 | 0.84 | KDM4E (0.35) | DAGLAABHD6HCRTR2HCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003993-A1 | PIPERIDINE DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-01-08 | — | — | WO | disclosed |