Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 8/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | ABHD11 | Q8NFV4 | 1/20 | 0.32 |
| ▸ | DAGLB | Q8NCG7 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150595 | 0.95 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL8151105 | 0.93 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL8138505 | 0.92 | DAGLA (0.35) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL8154720 | 0.91 | DAGLB (0.37) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL8149669 | 0.87 | DAGLA (0.34) | DAGLAABHD6HCRTR2HCRTR1NPC1 | |
| SCHEMBL8136051 | 0.86 | DAGLA (0.37) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL8136076 | 0.85 | KDM4E (0.38) | DAGLAABHD6HCRTR2HCRTR1DAGLB | |
| SCHEMBL7909447 | 0.85 | DAGLA (0.33) | DAGLAABHD6HCRTR2ABHD11MEN1 | |
| SCHEMBL8144465 | 0.84 | DAGLA (0.33) | DAGLAABHD6HCRTR2ABHD11DAGLB | |
| SCHEMBL8146211 | 0.83 | KDM4E (0.47) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003993-A1 | PIPERIDINE DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-01-08 | — | — | WO | disclosed |