Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | MAX | P61244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141574 | 0.89 | PDE1A (0.34) | CYP1A2CYP2D6HRH3ALDH1A1 | |
| SCHEMBL8142624 | 0.86 | HRH3 (0.34) | HRH3 | |
| SCHEMBL8148450 | 0.82 | ALDH1A1 (0.34) | CYP1A2CYP2D6HRH3ALDH1A1 | |
| SCHEMBL4036189 | 0.77 | PTGER4 (0.36) | — | |
| SCHEMBL8143985 | 0.72 | — | — | |
| SCHEMBL4033566 | 0.69 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL18153538 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL17735990 | 0.68 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL16304877 | 0.64 | AGTR1 (0.42) | ALDH1A1 | |
| SCHEMBL8135283 | 0.64 | KCNH2 (0.42) | CYP1A2CYP2D6HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127548-A | PREPARING OPTIONALLY SUBSTITUED 3H-IMIDAZOLE-4-CARBALDEHYDE BY PROTECTING THE 3-AMINO GROUP, THEN FORMYLATING IN PRESENCE OF AN ORGANOMETALLIC COMPOUND AND ELECTROPHILE WITH FORMYL LEAVING GROUP, DEPROTECTING WITH ACID OR STRONG BASE | LONZA AG (CH) | 2000-10-03 | — | — | US | disclosed |
| EP-0965590-A1 | Process for the preparation of formylimidazoles | LONZA A.G. (CH) | 1999-12-22 | — | — | EP | disclosed |