Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784920 | 0.76 | PDPK1 (0.33) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL1140881 | 0.67 | ACHE (0.41) | PDPK1GDALMNA | |
| SCHEMBL6930107 | 0.67 | ACHE (0.40) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL3350667 | 0.67 | PDPK1 (0.33) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL8149376 | 0.67 | PDPK1 (0.33) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL6244651 | 0.66 | ACHE (0.40) | PDPK1GDA | |
| SCHEMBL8136056 | 0.65 | TLR7 (0.49) | LMNA | |
| SCHEMBL1457529 | 0.64 | PDPK1 (0.33) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL5745701 | 0.63 | PDPK1 (0.46) | PDPK1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL3790459 | 0.61 | PDPK1 (0.41) | PDPK1GDAPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040112-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999029693-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |