Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRNE | Q04844 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140881 | 0.98 | ACHE (0.41) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL6930107 | 0.95 | ACHE (0.40) | ACHEMEN1MAPK1KMT2ABPTF | |
| SCHEMBL2707307 | 0.79 | NSD2 (0.40) | ACHEMAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL3350667 | 0.78 | PDPK1 (0.33) | PDPK1GDA | |
| SCHEMBL3350655 | 0.75 | UHRF1 (0.41) | NOS3NOS1NOS2PDPK1GDA | |
| SCHEMBL1457529 | 0.75 | PDPK1 (0.33) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5356574 | 0.70 | BCHE (0.41) | ACHEMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL4784920 | 0.69 | PDPK1 (0.33) | PDPK1GDA | |
| SCHEMBL8121994 | 0.67 | HPGD (0.50) | ACHEMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL1456870 | 0.66 | GABRA1 (0.38) | KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511746-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M Innovative Properties Company (US) | 2005-03-09 | — | — | EP | disclosed |
| US-6743920-B2 | CHORINATION REPLACING HYDROXYL GROUPS OF 2,4-DIHYROXY-3-NITROPYRIDINE DERIVATIVE; AMINATION, HYDROXYARYLATION, REDUCTION AND CYCLIZATION; AMINE REPLACEMENT OF PHENOXY FUNCTIONALITY | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-18 | — | — | US | disclosed |
| WO-2003101949-A2 | PROCESS FOR IMIDAZO[4,5-C]PYRIDIN-4-AMINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232852-A1 | Process for imidazo[4,5-c]pyridin-4-amines | CPNE4, HTR4, IL4 | ACHE 1268/4885MEN1 2947/4885MAPK1 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.