Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020881 | 0.90 | MAPT (0.51) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL5705535 | 0.89 | MAPT (0.50) | MAPTL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL7045154 | 0.88 | MAPT (0.56) | MAPTTP53KMT2AMEN1NPC1 | |
| SCHEMBL22969064 | 0.87 | MAPT (0.49) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL8741772 | 0.86 | TP53 (0.47) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL8142880 | 0.85 | PLA2G2A (0.54) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL8150632 | 0.85 | POLB (0.51) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL38661529 | 0.85 | PLA2G2A (0.54) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL7797045 | 0.84 | MAPT (0.48) | MAPTTP53THRBL3MBTL1KMT2A | |
| SCHEMBL8151119 | 0.84 | MAPT (0.55) | MAPTTP53THRBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018047-A | GROUP Z-A-AT POSITION 10, WHERE A IS A DIVALENT ORGANIC MOIETY AND Z IS CAPABLE OF COUPLING A BIOACTIVE COMPOUND, AND AT POSITION 9 AN ESTER WHICH FORMS DIOXETANE WITH HYDROGEN PEROXIDE; USE IN HETEROGENEOUS AND HOMOGENEOUS IMMUNOASSAYS | ZOMER GIJSBERT (NL) | 2000-01-25 | — | — | US | disclosed |
| US-5521103-A | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0324202-B1 | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARM CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| EP-0324202-A1 | Acridinium compounds as chemiluminogenic label | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |