Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | TACR3 | P29371 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020881 | 0.97 | MAPT (0.51) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL38661529 | 0.90 | PLA2G2A (0.54) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8142880 | 0.90 | PLA2G2A (0.54) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8741772 | 0.90 | TP53 (0.47) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8149705 | 0.87 | MAPT (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7536012 | 0.86 | KMT2A (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7787062 | 0.82 | DYRK1A (0.51) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8741771 | 0.82 | DYRK3 (0.48) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6584881 | 0.82 | KDM4E (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL22969068 | 0.82 | KDM4E (0.53) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040556-A1 | ACRIDINIUM ESTER-CONTAINING COMPOUNDS AND METHODS OF USING THE SAME FOR CHEMILUMINESCENCE-BASED ONE-COLOR SEQUENCING | MGI HOLDINGS CO., LIMITED (CN) | 2021-02-11 | — | — | US | disclosed |
| WO-2021023252-A1 | ACRIDINIUM ESTER-CONTAINING COMPOUNDS AND METHODS OF USING THE SAME FOR CHEMILUMINESCENCE-BASED ONE-COLOR SEQUENCING | BGI SHENZHEN CO., LTD. (CN) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040556-A1 | ACRIDINIUM ESTER-CONTAINING COMPOUNDS AND METHODS OF USING THE SAME FOR CHEMILUMINESCENCE-BASED ONE-COLOR SEQUENCING | ACR, CES2, PDE6C | MAPT 4464/4885NPC1 953/4885RAB9A 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.