Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | FNTA | P49354 | 13/20 | 0.39 |
| ▸ | FNTB | P49356 | 13/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3842211 | 0.99 | CYP19A1 (0.51) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| SCHEMBL8147489 | 0.82 | FNTA (0.48) | CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL7825652 | 0.78 | CYP19A1 (0.43) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL7841905 | 0.78 | CYP19A1 (0.43) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL7656506 | 0.75 | FNTA (0.45) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| SCHEMBL7826548 | 0.75 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| SCHEMBL3685047 | 0.75 | FNTA (0.49) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| SCHEMBL3499936 | 0.75 | FNTA (0.49) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL8544538 | 0.74 | FNTA (0.48) | CYP19A1FNTAFNTBPGGT1BHRAS | |
| Hydrochloric Acid SCHEMBL7834168 | 0.74 | FNTA (0.44) | CYP19A1FNTAFNTBPGGT1BHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1014984-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999009985-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |