Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143870 | 0.85 | ALOX5 (0.42) | MAPTALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL8143057 | 0.83 | KMT2A (0.45) | MAPTALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL8144608 | 0.76 | MAPT (0.37) | MAPTALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL8144613 | 0.76 | MAPT (0.41) | MAPTALDH1A1MAPK1LMNAHTT | |
| SCHEMBL6644428 | 0.75 | GAA (0.44) | MAPTALDH1A1MAPK1LMNATP53 | |
| SCHEMBL8141691 | 0.75 | HMGCR (0.41) | ALDH1A1LMNATDP1NPSR1HTT | |
| SCHEMBL8150112 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1MAPK1LMNATDP1 | |
| SCHEMBL19318503 | 0.73 | GAA (0.43) | MAPTALDH1A1MAPK1LMNATP53 | |
| SCHEMBL6638627 | 0.73 | SMN1; SMN2 (0.45) | MAPTALDH1A1MAPK1LMNATP53 | |
| SCHEMBL8151087 | 0.73 | MEN1 (0.50) | MAPTALDH1A1MAPK1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017918-A | Phenyl glycine compounds and methods of treating atherosclerosis and restenosis | WARNER-LAMBERT COMPANY (US) | 2000-01-25 | — | — | US | disclosed |