Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.71 |
| ▸ | MMP1 | P03956 | 10/20 | 0.71 |
| ▸ | MMP2 | P08253 | 6/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150208 | 1.00 | MMP3 (0.71) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6960997 | 0.84 | MMP3 (0.65) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6956792 | 0.83 | MMP3 (0.59) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL6963762 | 0.74 | MMP3 (0.72) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6957936 | 0.73 | MMP3 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL6961609 | 0.73 | MMP3 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL6958493 | 0.71 | MMP3 (0.69) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL6958185 | 0.71 | MMP3 (0.69) | MMP3MMP1MMP2MMP8MMP9 | |
| SCHEMBL6957197 | 0.71 | MMP3 (0.53) | MMP3MMP1MMP2CA1CA2 | |
| SCHEMBL6957782 | 0.69 | MMP3 (0.71) | MMP3MMP1MMP2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021424-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997048688-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |