Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.61 |
| ▸ | PPARA | Q07869 | 11/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874488 | 0.80 | PPARG (0.61) | PPARGPPARACNR1CNR2ACP3 | |
| SCHEMBL13923928 | 0.79 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL9423408 | 0.77 | CNR2 (0.61) | CNR1CNR2CASRACP3MTNR1A | |
| SCHEMBL1564807 | 0.76 | PPARA (0.59) | PPARGPPARA | |
| SCHEMBL9770359 | 0.76 | PPARG (0.67) | PPARGPPARAMTNR1AMTNR1BNPSR1 | |
| SCHEMBL14303460 | 0.75 | PPARG (0.54) | PPARGPPARACNR2ACP3L3MBTL1 | |
| SCHEMBL10419347 | 0.75 | PPARG (0.67) | PPARGPPARAL3MBTL1 | |
| SCHEMBL8935946 | 0.75 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL5508320 | 0.75 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL21991991 | 0.75 | PPARG (0.66) | PPARGPPARAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |