Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.61 |
| ▸ | PPARA | Q07869 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745447 | 0.88 | PPARG (0.66) | PPARGPPARASMN1; SMN2TSHRAKR1C3 | |
| SCHEMBL21991991 | 0.88 | PPARG (0.66) | PPARGPPARASMN1; SMN2TSHRAKR1C3 | |
| SCHEMBL16242008 | 0.88 | PPARG (0.66) | PPARGPPARASMN1; SMN2TSHRAKR1C3 | |
| SCHEMBL9198747 | 0.84 | PPARG (0.55) | PPARGPPARASMN1; SMN2KLK7TSHR | |
| SCHEMBL4651839 | 0.81 | SMN1; SMN2 (0.64) | PPARGPPARASMN1; SMN2TSHR | |
| SCHEMBL295888 | 0.81 | SMN1; SMN2 (0.64) | PPARGPPARASMN1; SMN2TSHR | |
| SCHEMBL8150263 | 0.80 | PPARG (0.61) | PPARGPPARAACP3L3MBTL1CNR2 | |
| Hydrochloric Acid SCHEMBL11617632 | 0.80 | SMN1; SMN2 (0.62) | PPARGPPARASMN1; SMN2TSHR | |
| SCHEMBL8935922 | 0.79 | SMN1; SMN2 (0.61) | PPARGPPARASMN1; SMN2TSHR | |
| SCHEMBL2364446 | 0.79 | PPARG (0.69) | PPARGPPARASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |