Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23640301 | 0.91 | KMT2A (0.49) | KMT2AL3MBTL1MEN1CYP2D6SMYD3 | |
| SCHEMBL8142546 | 0.87 | KMT2A (0.34) | KMT2AL3MBTL1MEN1MCHR1 | |
| SCHEMBL26617906 | 0.83 | ALDH1A1 (0.39) | KMT2AL3MBTL1MEN1LMNAMCHR1 | |
| SCHEMBL8138752 | 0.83 | HRH3 (0.41) | KMT2AMEN1LMNAMCHR1 | |
| SCHEMBL8144730 | 0.83 | HRH3 (0.41) | KMT2AMEN1LMNAMCHR1 | |
| SCHEMBL24680916 | 0.82 | USP30 (0.48) | KMT2AMEN1 | |
| SCHEMBL24680917 | 0.82 | USP30 (0.48) | KMT2AMEN1 | |
| SCHEMBL31208730 | 0.82 | USP30 (0.48) | KMT2AMEN1 | |
| SCHEMBL8145343 | 0.81 | MCHR1 (0.38) | KMT2AMEN1LMNAMCHR1 | |
| SCHEMBL8280857 | 0.79 | MCHR1 (0.46) | L3MBTL1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |