Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144730 | 1.00 | HRH3 (0.41) | HRH3L3MBTL3MCHR1MEN1KMT2A | |
| SCHEMBL13207157 | 0.90 | LTA4H (0.40) | HRH3L3MBTL3KMT2AALDH1A1LMNA | |
| SCHEMBL26617906 | 0.87 | ALDH1A1 (0.39) | L3MBTL3MCHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6111226 | 0.87 | HRH3 (0.43) | HRH3L3MBTL3MCHR1KMT2A | |
| SCHEMBL8145343 | 0.85 | MCHR1 (0.38) | L3MBTL3MCHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8280873 | 0.83 | MCHR1 (0.46) | HRH3L3MBTL3MCHR1ALDH1A1 | |
| SCHEMBL8280857 | 0.83 | MCHR1 (0.46) | HRH3L3MBTL3MCHR1ALDH1A1 | |
| SCHEMBL8147096 | 0.83 | CHRM4 (0.37) | L3MBTL3MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8150280 | 0.83 | KMT2A (0.45) | MCHR1MEN1KMT2ALMNA | |
| SCHEMBL8142546 | 0.81 | KMT2A (0.34) | L3MBTL3MCHR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |