Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150365 | 1.00 | PPARG (0.49) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL14681838 | 0.98 | PPARG (0.51) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL454223 | 0.94 | F7 (0.44) | PPARGPPARAMAPTBLMHSD17B10 | |
| SCHEMBL454225 | 0.94 | F7 (0.44) | PPARGPPARAMAPTBLMHSD17B10 | |
| SCHEMBL7110020 | 0.86 | PPARG (0.47) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL5228630 | 0.85 | TAS1R3 (0.47) | PPARGPPARAFAAHPTPN1 | |
| SCHEMBL5228623 | 0.85 | TAS1R3 (0.47) | PPARGPPARAFAAHPTPN1 | |
| SCHEMBL9231091 | 0.84 | PPARG (0.46) | PPARGPPARATERTMAPTBLM | |
| SCHEMBL15823600 | 0.83 | PPARG (0.39) | PPARGPPARAMAPTBLMHSD17B10 | |
| SCHEMBL11780651 | 0.83 | PPARG (0.39) | PPARGPPARAMAPTBLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017933-A | Mannich bases of conjugated styryl ketones | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 2000-01-25 | — | — | US | disclosed |