SCHEMBL454225

SCHEMBL454225

CCCCC=CC(=O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
PPARG P37231 2/20 0.42
PPARA Q07869 2/20 0.42
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
PTPN1 P18031 1/20 0.40
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
APEX1 P27695 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454223 1.00 F7 (0.44) F7F3PPARGPPARACNR1
SCHEMBL8150368 0.94 PPARG (0.49) F7F3PPARGPPARAPTPN1
SCHEMBL8150365 0.94 PPARG (0.49) F7F3PPARGPPARAPTPN1
SCHEMBL14681838 0.92 PPARG (0.51) F7F3PPARGPPARAPTPN1
SCHEMBL5228630 0.86 TAS1R3 (0.47) PPARGPPARACNR1CNR2PTPN1
SCHEMBL5228623 0.86 TAS1R3 (0.47) PPARGPPARACNR1CNR2PTPN1
SCHEMBL4611695 0.85 F7 (0.42) F7F3PPARGPPARACNR1
SCHEMBL4611690 0.85 F7 (0.42) F7F3PPARGPPARACNR1
SCHEMBL15823600 0.81 PPARG (0.39) PPARGPPARAGMNNUSP2LMNA
SCHEMBL11780651 0.81 PPARG (0.39) PPARGPPARAGMNNUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 913 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398341-B2 Apparatus and compositions for improving scent delivery THE PROCTER & GAMBLE COMPANY (US) 2025-08-26 US claimed
US-12247180-B2 Apparatus and compositions for improving scent delivery THE PROCTER & GAMBLE COMPANY (US) 2025-03-11 US claimed
EP-4106822-B1 COMPOSITION COMPRISING MICRO-ENCAPSULATED MALODOR CONTROL AGENTS AND THEIR USE FOR REDUCING MALODORS HENKEL AG & CO KGAA (DE) 2024-04-17 EP claimed
EP-3800184-B1 ACETAL / KETAL-BASED FRAGRANCE AND INSECT REPELLENT PRECURSOR COMPOUNDS HENKEL AG & CO KGAA (DE) 2024-04-03 EP claimed
US-20230099941-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING A NEUTRALIZING AGENT HENKEL AG & CO. KGAA (DE) 2023-03-30 US claimed
US-11542457-B2 Hydrolytically labile heterocycles of odoriferous ketones or odoriferous aldehydes HENKEL AG & CO. KGAA (DE) 2023-01-03 US claimed
EP-4106822-A1 BAD-ODOR CONTROL USING ENCAPSULATION TECHNOLOGIES CONTAINING NEUTRALIZING AGENT Henkel AG & Co. KGaA (DE) 2022-12-28 EP claimed
EP-3383359-B1 A FRAGRANCE COMPOSITION SYMRISE AG (DE) 2022-08-03 EP claimed
US-11352587-B2 Fragrance mixtures SYMRISE AG (DE) 2022-06-07 US claimed
US-20220002633-A1 APPARATUS AND COMPOSITIONS FOR IMPROVING SCENT DELIVERY THE PROCTER AND GAMBLE COMPANY 2022-01-06 US claimed
US-20120309669-A1 STABILIZED PERFUME OILS HENKEL AG & CO. KGAA (DE) 2012-12-06 US claimed
EP-1976855-B1 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES HENKEL AG & CO KGAA (DE) 2012-08-15 EP claimed
WO-2012084292-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE ALDEHYDE OR KETONE AND OXAZOLIDINE FRAGRANCE PRECURSOR HENKEL AG & CO. KGAA (DE) 2012-06-28 WO claimed
US-20110237685-A1 PHOTOLABILE FRAGRANCE STORAGE SUBSTANCES HENKEL AG & CO. KGAA (DE) 2011-09-29 US claimed
WO-2011101182-A1 STABILIZED PERFUME OILS HENKEL AG & CO. KGAA (DE) 2011-08-25 WO claimed
EP-1848702-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS Flexitral, Inc. (US) 2007-10-31 EP claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 US claimed
WO-2006085048-A2 PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS FLEXITRAL, INC. (US) 2006-08-17 WO claimed
EP-0141569-B1 PERFUMERY COMPOUNDS AND THEIR PREPARATION BUSH BOAKE ALLEN Limited (GB) 1988-12-21 EP claimed
EP-0141569-A2 Perfumery compounds and their preparation BUSH BOAKE ALLEN Limited (GB) 1985-05-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309669-A1 STABILIZED PERFUME OILS CUTA, ALB, AADAT F7 606/4885F3 1236/4885PPARG 362/4885
US-11542457-B2 Hydrolytically labile heterocycles of odoriferous ketones or odoriferous aldehydes CAT, AOX1, HOGA1 F7 1299/4885F3 2595/4885PPARG 2422/4885
US-11352587-B2 Fragrance mixtures DHCR24, FAM120A, TRPA1 F7 3079/4885F3 2834/4885PPARG 192/4885
US-20110237685-A1 PHOTOLABILE FRAGRANCE STORAGE SUBSTANCES TRPA1, NISCH, ALDH18A1 F7 2342/4885F3 2788/4885PPARG 1005/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 F7 236/4885F3 2183/4885PPARG 500/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.