Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.77 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158265 | 0.89 | MTNR1A (0.78) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL8137831 | 0.87 | MTNR1A (0.78) | MTNR1AMTNR1B | |
| SCHEMBL8135627 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL6075502 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7019542 | 0.84 | MTNR1A (0.69) | MTNR1AMTNR1B | |
| SCHEMBL25028266 | 0.80 | MTNR1A (0.67) | MTNR1AMTNR1BMPOCYP1A2 | |
| SCHEMBL9123376 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL25030269 | 0.80 | MTNR1B (0.70) | MTNR1AMTNR1BMEN1KMT2AKDM4E | |
| SCHEMBL8152799 | 0.77 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL855990 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1BMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737685-B1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-07-19 | — | — | EP | disclosed |
| EP-0737685-A1 | Pyridine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |