Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.55 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8152728 | 0.95 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL7256501 | 0.86 | TDP1 (0.56) | MAPTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL7256510 | 0.86 | TDP1 (0.56) | MAPTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL18993851 | 0.83 | AKR1B10 (0.44) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL18347589 | 0.81 | AKR1B10 (0.44) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL8157084 | 0.81 | TDP1 (0.64) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4592405 | 0.81 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ALY96 | |
| SCHEMBL4592398 | 0.81 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ALY96 | |
| SCHEMBL8143972 | 0.80 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2AAKR1B10 | |
| SCHEMBL2226678 | 0.80 | MAPT (0.59) | MAPTALDH1A1MEN1KMT2AAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |