SCHEMBL8150871

SCHEMBL8150871

CN1C(=O)NC(=O)C1Cc1ccc(Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.48
CAPN1 P07384 1/20 0.44
PPARG P37231 1/20 0.41
MMP2 P08253 1/20 0.39
MDM2 Q00987 2/20 0.38
TSHR P16473 1/20 0.38
CMA1 P23946 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7097780 0.83 GFER (0.66) GFERCAPN1
SCHEMBL25385021 0.78 CAPN1 (0.46) GFERCAPN1PPARGMMP2
SCHEMBL31319111 0.72 CAPN1 (0.50) GFERCAPN1PPARGMMP2MDM2
SCHEMBL25367152 0.72 NPSR1 (0.46) PPARGTSHR
SCHEMBL18577397 0.69 GHSR (0.48)
SCHEMBL18589459 0.69 GHSR (0.48)
SCHEMBL20747194 0.69 GHSR (0.48)
SCHEMBL15180968 0.69 MAPT (0.48) PPARGTSHR
SCHEMBL11289816 0.69 GRM2 (0.41) PPARG
SCHEMBL13399537 0.69 MDM2 (0.47) PPARGMMP2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000327665-A ALKYLHYDANTOIN COMPOUND MITSUBISHI CHEMICALS CORP 2000-11-28 JP disclosed