Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150871 | 0.83 | GFER (0.48) | GFERCAPN1 | |
| SCHEMBL30670504 | 0.80 | GFER (1.00) | GFERPLA2G10PLA2G5MMP1MMP3 | |
| SCHEMBL25937447 | 0.77 | CAPN1 (0.67) | GFERPLA2G10PLA2G5MMP1MMP3 | |
| SCHEMBL23873935 | 0.77 | CAPN1 (0.67) | GFERPLA2G10PLA2G5MMP1MMP3 | |
| SCHEMBL2984273 | 0.77 | GFER (0.49) | GFERDDB1CRBNMMP1MMP3 | |
| SCHEMBL6922838 | 0.77 | GFER (0.56) | GFERDDB1CRBNPLA2G10PLA2G5 | |
| SCHEMBL8789899 | 0.77 | GFER (0.56) | GFERDDB1CRBNPLA2G10PLA2G5 | |
| SCHEMBL24491235 | 0.74 | GFER (0.50) | GFERDDB1CRBNPLA2G10PLA2G5 | |
| SCHEMBL29289313 | 0.74 | ALDH1A1 (0.44) | GFERDDB1CRBN | |
| SCHEMBL11422960 | 0.73 | GFER (0.46) | GFERDDB1CRBNHDAC8CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| EP-0725142-B1 | PROCESS FOR PRODUCING D-AMINO ACID BY USING COMPOSITE IMMOBILIZED ENZYME PREPARATION | KANEGAFUCHI CHEMICAL IND (JP) | 2003-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | GFER 938/4885DDB1 560/4885CRBN 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.