Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8157309 | 0.92 | CA1 (0.40) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8150711 | 0.89 | MEN1 (0.44) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8157301 | 0.89 | GRIK1 (0.44) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8158359 | 0.88 | POLB (0.41) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8156581 | 0.88 | POLB (0.47) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8381971 | 0.86 | POLB (0.45) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8153306 | 0.85 | POLB (0.51) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8157213 | 0.85 | POLB (0.43) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8153415 | 0.85 | ALOX5 (0.42) | HTTPOLBAPEX1TDP1ALOX5 | |
| SCHEMBL8158364 | 0.84 | TDP1 (0.39) | HTTPOLBAPEX1TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |