Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8156926 | 0.93 | MEN1 (0.40) | TDP1HTTPOLBAPEX1MEN1 | |
| SCHEMBL8157860 | 0.87 | GLO1 (0.52) | MEN1KMT2AFBP1KDM4ESMN1; SMN2 | |
| SCHEMBL8151217 | 0.84 | HTT (0.43) | TDP1HTTPOLBAPEX1MEN1 | |
| SCHEMBL8158569 | 0.84 | TDP1 (0.43) | TDP1HTTPOLBAPEX1KMT2A | |
| SCHEMBL8157301 | 0.83 | GRIK1 (0.44) | TDP1HTTPOLBAPEX1ALOX5 | |
| SCHEMBL8150711 | 0.83 | MEN1 (0.44) | TDP1HTTPOLBAPEX1MEN1 | |
| SCHEMBL8153015 | 0.83 | MAPT (0.43) | HTTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8158359 | 0.82 | POLB (0.41) | TDP1HTTPOLBAPEX1MEN1 | |
| SCHEMBL8156581 | 0.82 | POLB (0.47) | TDP1HTTPOLBAPEX1KMT2A | |
| SCHEMBL8381971 | 0.81 | POLB (0.45) | TDP1HTTPOLBAPEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |