SCHEMBL8152192

SCHEMBL8152192

CCCCC(=O)OCCCC(=O)OCI

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.59
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
DNM1 Q05193 1/20 0.49
NAAA Q02083 1/20 0.48
HTR2C P28335 1/20 0.47
TSHR P16473 2/20 0.44
ATM Q13315 2/20 0.44
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PAM P19021 2/20 0.44
ALDH1A1 P00352 3/20 0.43
MGLL Q99685 1/20 0.42
MAPT P10636 2/20 0.42
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
THRB P10828 1/20 0.41
CNR1 P21554 1/20 0.41
EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680864 0.92
SCHEMBL26116111 0.86 DGKA (0.61) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL6893576 0.85 DGKA (0.65) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL130610 0.85 DGKA (0.71) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL812772 0.85 DGKA (0.71) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL11270665 0.85 DGKA (0.71) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL3502464 0.85 DGKA (0.71) DGKAPRSS1PRSS2PRSS3DNM1
Chloroform SCHEMBL8309332 0.84 TSHR (0.49) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL2529870 0.83 DGKA (0.63) DGKAPRSS1PRSS2PRSS3DNM1
SCHEMBL2217057 0.83 DGKA (0.69) DGKAPRSS1PRSS2PRSS3DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0593595-B1 DERIVATIVES OF INOSITOL, PREPARATIONS CONTAINING THEM AND THEIR USE PERSTORP AB (SE) 2000-01-05 EP disclosed
EP-0593595-A1 DERIVATIVES OF INOSITOL, PREPARATIONS CONTAINING THEM AND THEIR USE PERSTORP AB (SE) 1994-04-27 EP disclosed
US-5306841-A Derivatives of inositol, preparations containing them and their use BUNDGAARD HANS (DK) 1994-04-26 US disclosed
WO-1993001197-A1 DERIVATIVES OF INOSITOL, PREPARATIONS CONTAINING THEM AND THEIR USE PERSTORP AB (SE) 1993-01-21 WO disclosed