⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893576 | 0.93 | DGKA (0.65) | — | |
| SCHEMBL8152192 | 0.92 | DGKA (0.59) | — | |
| Chloroform SCHEMBL8309332 | 0.92 | TSHR (0.49) | — | |
| SCHEMBL2181324 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL2145671 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL2217057 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL355564 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL31112831 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL2182828 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL2183449 | 0.91 | DGKA (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250215030-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. | 2025-07-03 | — | — | US | disclosed |
| EP-4499656-A1 | STAT MODULATORS AND USES THEREOF | Recludix Pharma, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-114364665-B | Prodrugs for modulating interleukins | 百时美施贵宝公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-119183453-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| WO-2023192960-A1 | STAT MODULATORS AND USES THEREOF | RECLUDIX PHARMA, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| CN-101998961-B | Substituted 2-phenyl-pyridine derivatives | ACTELION PHARMACEUTICALS LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-101868469-B | Phosphonic acid derivatives and their use as P2Y12Receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2014-04-02 | — | — | CN | disclosed |
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0790235-A1 | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses | SANKYO COMPANY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |
| CN-1029961-C | Benzimidazole derivatives, their prodn. and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |
| CN-1051355-A | Benzimidizole derivatives, its production method and application thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-05-15 | — | — | CN | disclosed |