Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | NCF1 | P14598 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540903 | 0.82 | SMN1; SMN2 (0.46) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL31325635 | 0.82 | SMN1; SMN2 (0.46) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL28628097 | 0.74 | MEN1 (0.56) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL4278377 | 0.74 | CYP1A2 (0.47) | MEN1MAPTKMT2ANCF1NOS2 | |
| SCHEMBL6607250 | 0.74 | MEN1 (0.51) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL9663555 | 0.71 | MAPT (0.61) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL6600702 | 0.71 | MEN1 (0.56) | MEN1MAPTKMT2AHDAC1HDAC8 | |
| SCHEMBL1131286 | 0.71 | NCF1 (0.50) | MEN1MAPTKMT2ANCF1NOS2 | |
| SCHEMBL31498821 | 0.71 | NCF1 (0.50) | MEN1MAPTKMT2ANCF1NOS2 | |
| SCHEMBL2744806 | 0.70 | CYP1A2 (0.42) | MEN1MAPTKMT2ANCF1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009748-A1 | 3-ALKYLPYRROLO 3,2-$i(c)]QUINOLINE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2000-06-21 | — | — | EP | disclosed |
| WO-2000001696-A1 | 3-ALKYLPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-13 | — | — | WO | disclosed |