Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.55 |
| ▸ | THRB | P10828 | 8/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600377 | 1.00 | THRA (0.55) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL10600396 | 0.98 | THRA (0.53) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL8303752 | 0.86 | GRIN2D (0.67) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL7342564 | 0.86 | GRIN2D (0.67) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL7331987 | 0.86 | GRIN2D (0.67) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL2403600 | 0.86 | GRIN2D (0.67) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL12065208 | 0.85 | THRA (0.73) | THRATHRBRARBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10716592 | 0.85 | GRIN2D (0.65) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL10081274 | 0.84 | GRIN2D (0.68) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL1020543 | 0.84 | THRA (0.70) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000327667-A | AZACROWN DERIVATIVE | CANON INC | 2000-11-28 | — | — | JP | disclosed |